Interaction of Hepatitis C virus proteins with pattern recognition receptors
نویسندگان
چکیده
منابع مشابه
The Absence of Hepatitis C Virus Infection Among Patients with Hepatitis B virus in Mashhad, Iran
Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...
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Background: Hepatitis C virus (HCV) infection is one of the most prevalent infectious diseases responsible for high morbidity and mortality worldwide. Therefore, designing new and effective therapeutics is of great importance. The aim of the current study was to construct a DNA vaccine containing structural proteins of HCV and evaluation of its expression in a eukaryot...
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Introduction Innate immunity has a key role in combating microbial infections in all animals. The innate immune response is activated by receptors known as pattern recognition receptors (PRRs), which recognize surface determinants that are conserved among microbes but are absent in the host, including components such as lipopolysaccharides (LPSs), peptidoglycans (PGs) and mannans (Medzhitov & J...
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Nowadays viral hepatitis is one of the most common and important causes of chronic liver disorders in the world. Extrahepatic manifestations of viral hepatitis consist a main part of the disease. The main viruses causing hepatitis include Hepatitis A, B and C viruses. Herein common skin manifestations in hepatitis C virus (HCV) are discussed. Chronic hepatitis causes skin disorders both directl...
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Chronic hepatitis C virus (HCV) infection is a major risk factor for liver disease progression, and may lead to cirrhosis and hepatocellular carcinoma (HCC). The HCV genome contains a single-stranded positive sense RNA with a cytoplasmic lifecycle. HCV proteins interact with many host-cell factors and are involved in a wide range of activities, including cell cycle regulation, transcriptional r...
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ژورنال
عنوان ژورنال: Virology Journal
سال: 2012
ISSN: 1743-422X
DOI: 10.1186/1743-422x-9-126